Abstract
An: 2017, Nr.2, Articol Nr. 10
Title: 

A NEW CASE OF HEREDITARY GINGIVAL FIBROMATOSIS

Authors: 

      Lavinia Caba, Mihaela Grămescu, Monica Pânzaru, Lăcrămioara Butnariu, Roxana Popescu, Irina Resmeriţă, E.V. Gorduza - “Grigore T. Popa” University of Medicine and Pharmacy, Iasi, Romania, Medical Genetics Department
      Carmen Ungureanu - “Grigore T. Popa” University of Medicine and Pharmacy, Iasi, Romania, Morphopathology Department
      Hamwi Saad - “St. Spiridon” Hospital, Iasi, Romania, Oral and Maxillofacial Surgery Department
      A NEW CASE OF HEREDITARY GINGIVAL FIBROMATOSIS (Abstract): Hereditary gingival fibromatosis is a rare disease characterized by various degrees of attached gingival overgrowth. It can be isolated or be part of some syndromes, the isolated form being sporadic or familial with autosomal dominant pattern of transmission. Our patient is a female with moderate gingival enlargement firm on palpation and with normal color. Both mandible and maxilla are involved and have functional impairment (the speech and mastication affected). The onset of the disease was in childhood during the eruption of permanent dentition and the patient was treated by repeated gingivectomy procedures. The personal history rules out the use of medications involved in gingival enlargement. Family history was positive for gingival overgrowth consistent with dominant inheritance. The syndromes with gingival fibromatosis were excluded. The patient was surgically treated and the histological features are consistent with gingival fibromatosis. The complex management includes gingivectomy for functional improvement of speech and mastication. Also, it is important to identify the isolated form or the syndromic one in order to provide appropriate genetic counseling.
Key words: HEREDITARY GINGIVAL FIBROMATOSIS, GINGIVECTOMY
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