Abstract
An: 2017, Nr.3, Articol Nr. 5
Title: 

EMBRYOLOGIC DEVELOPMENT AND KNEE MALFORMATIONS

Authors: 

      Milena Toncea - University of Medicine and Pharmacy, Bucharest, Phd (Doctoral School)
      F.M. Filipoiu - University of Medicine and Pharmacy, Bucharest, Department of Anatomy
      EMBRYOLOGIC DEVELOPMENT AND KNEE MALFORMATIONS. REVIEW OF LITERATURE DATA (Abstract): The embriologic development of the lower limb, including here the development of the knee, it is known to be between 6-8 weeks postovulatory when we can identify the differentiation of the main joint cavities (synovial, cartilaginous, fibro-cartilaginous). During chondrogenesis proteoglicans like versican, tenascin C, aggrecan and hyaluronic acid play a major role and they are well represented in pericondrum. I followed to present the very important stages of the knee development and the same for the malformations of the lower limb. Studying some dissections of human embryos classified with Carnegie (Streeter) stages, and some scientific publications we try to understand better the main cavitation mechanism of the lower limb and the knee, anatomic element structured with the developpement of the femur, patella, tibia and fibula. The developpement disorders of these structures imply congenital patellar syndrome without significant changes in the static of the lower limb, proximal focal femoral deficiency, congenital short femur, tibial/peroneal hemimelia, congenital bowing of the knee.
Key words: JOINT, KNEE, EMBYOS, MALFORMATIONS
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