Abstract
An: 2015, Nr.2, Articol Nr. 6
Title: 

STUDY OF THE DEVELOPMENT OF MIDLINE SKULL BASE SYNCHONDROSES USING COMPUTED TOMOGRAPHY

Authors: 

      Balint Andrea, Baróti Beáta Ágota, M. Buruian - Emergency Clinical County Hospital Targu Mures, Radiology and Medical Imaging Laboratory
      Pap Zsuzsanna, Pávai Zoltán - University of Medicine and Pharmacy Targu Mures, Department of Anatomy and Embryology
      STUDY OF THE DEVELOPMENT OF MIDLINE SKULL BASE SYNCHONDROSES USING COMPUTED TOMOGRAPHY (Abstract): Aim: Cranial base synchondroses are important growth centers of the craniofacial development. The aim of the present study is to evaluate the development of the midline synchondroses, determining the sequence and timing of closure of the spheno-ethmoid, intersphenoid and spheno-occipital synchondrosis, based on computed tomography (CT) scans. Materials and methods: We studied retrospectively 88 patients aged 0 to 25 years, who underwent head CT in Targu Mures Emergency County Hospital, with no known diseases that would affect skull base development. 10 fetal specimens, aged 14 to 23 gestational weeks, from the Museum of Anatomy and Embriology (University of Medicine and Farmacy Targu Mures) were also included in our study. We assessed: the ossification status of the synchondrosis (open, partially closed and closed); the diameter of the unfused spheno-occipital synchondrosis; the location and time of appearance of the ossification center in the synchondroses; time of fusion of the synchondroses; skull base lengths. Results: The spheno-ethmoidal synchondrosis was closed above the age of 5 and the intersphenoid in all patients aged 3 or older. The earliest complete closure of the spheno-occipital synchondrosis was noted at 11 years in girls and 16 years in boys. The synchondrosis was closed in all girls older than 16 and boys older than 17. Persistency of a scar at the site of fusion was noted until the age of 24 years. Conclusions: Closure of the intersphenoid synchondrosis occurs later, while the sphenoethmoidal earlier than it was previously known. The spheno-occipital synchondrosis closed earlier in girls.
Key words: SKULL BASE, SYNCHONDROSIS, DEVELOPMENT, CT
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