Abstract
An: 2013, Nr.2, Articol Nr. 2
Title: 

VILLOUS CYTOTROPHOBLAST TURNOVER. IMPLICATIONS IN ORTHOLOGY AND PATHOLOGY OF GESTATION

Authors: 

      Elena Patrascu, Gh.S. Dragoi - University of Medicine and Pharmacy Craiova, Romania, 1st Department – Morphological Sciences
      VILLOUS CYTOTROPHOBLAST TURNOVER. IMPLICATIONS IN ORTHOLOGY AND PATHOLOGY OF GESTATION (Abstract): The authors proposed themselves to evaluate the phenotype changes of the structural elements forming placenta villi based on the concept of “cellular turn over”. The research has been carried out on first and third trimester of gestation placentas. Based on their personal observations they considered that trophoblast cells maintain its homeostasis by means of proliferation, differentiation and apoptosis, contributing to the formation of syncytiotrophoblast layer during placenta evolution. In pathology, trophoblast proliferation is accelerated by processes accompanied by hypoxia.
Key words: CELLULAR TURN OVER, CYTOTROPHOBLAST, PHENOTYPE CHANGES, HYPOXIA.
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