Abstract
An: 2011, Nr.2, Articol Nr. 23
Title: 

THE ROLE OF MACROPHAGE IN THE ANGIOGENESIS OF BREAST CANCER

Authors: 

      Simona Partene Vicoleanu - “Gr.T. Popa” University of Medicine And Pharmacy, Iaşi, Ph.D student, Faculty of Medicine, Department of Immunology
      THE ROLE OF MACROPHAGE IN THE ANGIOGENESIS OF BREAST CANCER (Abstract): Tumor associated cells such as inflammatory cells, endothelial cells and stromal cells, interact with cancer cells. Cancer cells are also able to escape and to use the normal inflammatory cells in order to enhance tumoral progression through neoangiogenesis and metastasis. The present study wants to make a correlation between the degree of infiltration with macrophages and the development of the tumor. All cancerous tumors release angiogenic growth factor proteins that stimulate blood vessels to grow into the tumor, providing it with oxygen and nutrients. Anti-angiogenic therapies literally starve the tumor of its blood supply by interfering with this process and seem to be the future of the therapy of breast cancer.
Key words: BREAST CANCER, NEOANGIOGENESIS, IMMUNE INFILTRATE, MACROPHAGE, CYTOKINES
archive
Current edition
2021
Previous editions