Abstract
An: 2018, Nr.2, Articol Nr. 9
Title: 

AORTIC VALVE SCLEROSIS – MORE THAN A SIMPLE ANATOMIC ABNORMALITY: LITERATURE REVIEW

Authors: 

      E.M. Mihu - Emergency Clinical County Hospital, Craiova
      A.C. Nechita, R.L. Ploesteanu, S.C. Stamate - “Sf. Pantelimon Clinical” Clinical Emergency Hospital, Bucharest; “Carol Davila” University of Medicine and Pharmacy, Bucharest, Faculty of Medicine
      I.T. Nanea - “Carol Davila” University of Medicine and Pharmacy, Bucharest, Faculty of Medicine; “Prof. Dr. Theodor Burghele” Hospital, Bucharest
      AORTIC VALVE SCLEROSIS – MORE THAN A SIMPLE ANATOMIC ABNORMALITY: LITERATURE REVIEW (Abstract): Introduction: Anatomic abnormality until recently considered benign entity, aortic valve sclerosis represents the thickening and calcification of the aortic valve, with a maximum transvalvular velocity between 1.5 m/sec and 2.5 m/sec (1) (doppler echocardiography assessment). The aim of our systematic review is to summarize the importance of this anatomic abnormality, its early echocardiographic diagnosis and the association of various comorbidities. Although aortic valve sclerosis is asymptomatic, in time it is associated with increased mortality through its evolution towards symptomatic aortic stenosis and through its association with increased risk of myocardial infarction, risk of stroke and cardiovascular death. Material and Methods: We performed an extensive research on different literature databases regarding aortic valve sclerosis and calcific aortic disease. The selected data contains information about aortic valve anatomy, risc factors leading to aortic valve calcification, comorbidities associated with aortic valve sclerosis and aortic valve sclerosis progression. Results: Cardiovasular risk factors are common in patients with aortic valve sclerosis and patients with aortic sclerosis associate multiple comorbidities. In time, aortic valve sclerosis progresses to simptomatic aortic stenosis. Conclusions: As the development of aortic sclerosis is silent, this anatomical change has long been neglected and considered irrelevant. The association with multiple comorbidities and the evolution to clinically manifest aortic stenosis transform the aortic sclerosis into a marker of complex cardiovascular pathology.
Key words: AORTIC VALVE SCLEROSIS, CALCIFIC AORTIC DISEASE, ECOCARDIOGRAPHY
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