Abstract
An: 2015, Nr.3, Articol Nr. 33
Title:
PATHOPHYSIOLOGICAL CORRELATIONS IN GASTRO-INTESTINAL LYMPHOMAS
Authors:
Petruţa Jantea, Corina Silvia Pop - “Carol Davila” University of Medicine and Pharmacy, Bucharest; Emergency University Hospital Bucharest, Medical Clinical and Gastroenterology
Ana-Maria Vlădăreanu - “Carol Davila” University of Medicine and Pharmacy, Bucharest; Emergency University Hospital Bucharest, Hematology Clinic
Roxana Maria Nemeş - “Carol Davila” University of Medicine and Pharmacy, Bucharest; “Marius Nasta” National Institute of Pneumology Bucharest
Camelia Dobrea - “Carol Davila” University of Medicine and Pharmacy, Bucharest; Onco Team Diagnostic Bucharest
PATHOPHYSIOLOGICAL CORRELATIONS IN GASTRO-INTESTINAL LYMPHOMAS (Abstract): Lymphomas represents neoplasms of the lymph reticular system (including Peyer’s patches) and the gastrointestinal tract is the most commonly involved extranodal site. Lymphoma’s incidence rised in past four decades so in this moment all extranodal lymphomas represent 30-40% from all Non-Hodgkin lymphomas. The stomach is the common site of GIT lymphomas (>85%) represented by mucosa associated lymphoid tissue (MALT), a indolent disease and diffuse large B-cell Lymphoma (DCBCL), a type of aggressive malignancy. Follicular lymphoma (FL), mantle cell lymphoma (MCL), small lymphocytic lymphoma (SLL), T-cell lymphoma (TCL) and plasmacytoma are very rare in the stomach. Lyphomas are localized on small intestine because it contains a lot of mucosal lymphoid tissue represented both by B- and T-cells such that immunocompromised patients can have reactive lymphohistiocytic infiltrates secondary to infections that can occur or mimic Hodgkin lymphoma. Burkitt lymphomas are often found on children and DLBC lymphomas are the commonest on adults.
Key words: LYMPHOMA, GASTROINTESTINAL, ENDOSCOPY, MALT, B-, T-CELL