An: 2012, Nr.3, Articol Nr. 14

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      ANATOMICAL CHARACTERISTICS OF ISCHEMIC HEART DISEASE IN WOMEN WITH TYPE 2 DIABETES MELLITUS. ORIGINAL COMMUNICATION (Abstract): BACKGROUND: Diabetes mellitus is associated with a markedly increased prevalence of coronary artery disease wich is as high as 55% among adult patients with diabetes compared with 2% to 4% for the general population. OBJECTIVE: To evaluate the anatomical characteristics of ischemic heart disease in women with type 2 diabetes mellitus. MATERIAL AND METHOD: A retrospective, case control study performed by comparative analysis of anamnestical, clinical and coronary angiography data of 156 women angiographycally investigated for ischemic heart disease that were divided according to the presence of diabetes into 2 groups with similar age distribution. RESULTS: The diabetic women more frequently presented coronary lesions compared to controls (84.62% versus 74.36%, p = 0.01). The coronary artery disease was more severe with a high prevalence of three vessel disease (34.62% versus 19.23%). Diabetic women had more frequently indication of surgical myocardical revascularization (11.53% versus 4.35%, p = 0.02) and more frequently needed angiographic reintervention for in stent restenosis (7.7%). CONCLUSIONS: Diabetic women with ischemic heart disease had more severe coronary artery disease, more commonly presented post angiographic complications and often required surgical myocardial revascularization techniques.

Key words: CORONARY ARTERY DISEASE, CORO-NAROGRAPHY, ANGIOPLASTY