Abstract
An: 2024, Nr.2, Articol Nr. 3
Title:
INFLUENCE OF MEDIAN DIAMETERS OF ARTERIES FORMING THE CIRCLE OF WILLIS ON IN-HOSPITAL MORTALITY IN STROKE PATIENTS – AN AUTOPSIC STUDY
Authors:
Ana-Maria Dumitrescu, G.C. Moroşan, Ruxandra Vatavu, Roxana Florentina Şufaru, C.I. Stan - „Grigore T. Popa” University of Medicine and Pharmacy, Iasi, Romania, Department of Morphofunctional Sciences I
Anca Sava, Veronica Scripcaru - „Grigore T. Popa” University of Medicine and Pharmacy, Iasi, Romania, Department of Morphofunctional Sciences I; „Prof. Dr. N. Oblu” Emergency Clinical Hospital, Iasi, Romania, Department of Pathology
INFLUENCE OF MEDIAN DIAMETERS OF ARTERIES FORMING THE CIRCLE OF WILLIS ON IN-HOSPITAL MORTALITY IN STROKE PATIENTS – AN AUTOPSIC STUDY (Abstract): Purpose: to realize a comparative analysis of demographic characteristics and outer diameters of the arteries of the circle of Willis (CW) according to the presence/absence of ischemic stroke. Material and methods: We performed a retrospective study on 166 adult patients, hospitalized in „Prof. dr. N. Oblu” Emergency Clinical Hospital from Iaşi, in the period of 12 years, who died during hospitalization and on whom an autopsy was performed in order to determine the cause of death. The subjects were divided into 2 groups: (1). 48 patients without stroke; (2) 118 patients with ischemic stroke. Demographic data, causes of death, and outer diameters of CW arteries were collected and compared between the two groups of patients. Results: Patients with ischemic stroke were older (67.49±12.96 years) compared to those without stroke (60.33±15.67 years). 61.8% of ischemic stroke patients were male, and non-stroke patients were predominantly female (60.4%). 58.5% of those with ischemic stroke and 64.6% of patients without stroke came from rural areas. The median diameter (mD) of the ACoA was statistically significantly lower in patients with ischemic stroke (1.10 mm) compared to the others (1.40 mm); mD of right ACA was lower in patients with ischemic stroke (1.70 mm) compared to patients without stroke (1.80 mm). mD of right and left PCoAs were statistically significantly smaller in patients with ischemic stroke (0.30 mm, each) compared to those without stroke (0.60 mm, each). mD of right and left PCoAs were similar in both groups of patients (1.90 mm). Conclusions: The present research found that ischemic stroke patients were elderly, predominantly of male gender, and expressed a reduction of the external diameters of the anterior communicating artery, right anterior cerebral artery, right and left posterior communicating arteries, while patients without stroke did not show such vascular morphological changes.
Key words: ARTERIAL DIAMETER, CIRCLE OF WILLIS, ISCHEMIC STROKE
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