Abstract
An: 2020, Nr.4, Articol Nr. 2
Title:
AMYGDALOID COMPLEX AS THE „ORGAN” OF ANXIETY: ITS ANATOMY, MICROSCOPY ANF FUNCTIONS. A REVIEW
Authors:
Anca Sava - „Grigore T. Popa” University of Medicine and Pharmacy, Iaşi, Romania, Morpho-Functional Sciences I; „Prof. dr. N. Oblu” Emergency Clinical Hospital, Iaşi, Romania, Department of Pathology
Ş. Turliuc - „Grigore T. Popa” University of Medicine and Pharmacy, Iaşi, Romania, Department of Medical III; „Socola” Institute of Psychiatry, Iaşi, Romania
C.I. Stan - „Grigore T. Popa” University of Medicine and Pharmacy, Iaşi, Romania, Morpho-Functional Sciences I
Dana Mihaela Turliuc - „Grigore T. Popa” University of Medicine and Pharmacy, Iaşi, Romania, Department of Surgery II; „Prof. dr. N. Oblu” Emergency Clinical Hospital, Iaşi, Romania, IInd Neurosurgery Clinic
A.I. Cucu - „Prof. dr. N. Oblu” Emergency Clinical Hospital, Iaşi, Romania, IInd Neurosurgery Clinic
Nicoleta Dumitrescu - „Socola” Institute of Psychiatry, Iaşi, Romania
G.C. Moroşan, A.D. Costache - „Grigore T. Popa” University of Medicine and Pharmacy, Iaşi, Romania, Doctoral School
Claudia Florida Costea - „Grigore T. Popa” University of Medicine and Pharmacy, Iaşi, Romania, Department of Surgery II; „Prof. dr. N. Oblu” Emergency Clinical Hospital, Iaşi, Romania, IInd Ophthalmology Clinic
AMYGDALOID COMPLEX AS THE „ORGAN” OF ANXIETY: ITS ANATOMY, MICROSCOPY ANF FUNCTIONS. A REVIEW (Abstract): From an anatomical point of view, the amygdaloid complex is a nervous structure still incompletely known both in terms of its extent, number and classification of its subdivisions, but also in terms of its microscopic structure, along with its functions, which seem to be much more more complex than previously known. For this reasons, in this article we will try to present the history of the identification of amygdala as an anatomical structure, but also we will identify a model of amygdala architecture based on recent data on macro- and microanatomy, as well as on its functions. To date, there are many attempts to classify the numerous amygdalar nuclei, but this can be a difficult task as these nuclei have many subdivisions. The terminology used to describe the amygdala nuclei differs from author to author and from one atlas to another. Immunohistochemistry has shown that the amygdala is made up of GABA-positive neurons (GABA-neurons), which are located ventrally, in the central amygdala nucleus and in the medial amygdalar nucleus, and terminate along the ventromedial edge of the cerebral hemisphere, but there are also glutamatergic neurons, suggesting that the amygdala is a mixed, striatal, and cortical structure. Regarding its functions, the amygdaloid complex is the only nervous structure capable of processing sensory information and initiating the behavioral response before the information of a threatening reaches the awareness centers in the cerebral cortex. It is important to emphasize that in the field of psychiatry the amygdaloid complex is of vital importance because the complete knowledge of its structure and functions can help in finding the most appropriate treatments for certain psychiatric diseases.
Key words: AMYGDALOID COMPLEX, ANATOMY, IMMUNOHISTOCHEMISTRY, ANXIETY
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