Abstract
An: 2019, Nr.4, Articol Nr. 6
Title: 

IMMUNOTHERAPY IN BREAST CANCER. THE SPATIAL ORGANIZATION OF INFLAMMATORY INFILTRATE

Authors: 

      Simona-Alice Partene Vicoleanu, A.H. Nedelcu, M. Moraru, G. Stătescu, S. Luchian, C.I. Stan - “Grigore T. Popa” University of Medicine and Pharmacy, Iaşi, Department of Morphofunctional Science I
      C.M. Buzdugă - “Grigore T. Popa” University of Medicine and Pharmacy, Iaşi, Department of Endocrinology
      IMMUNOTHERAPY IN BREAST CANCER.THE SPATIAL ORGANIZATION OF INFLAMMATORY INFILTRATE (Abstract): Breast cancer progression is associated with robust neovascularization. The tumour-associated ‘normal’ cells, such as immune/inflammatory cells, endothelial cells and stromal cells, conspire with cancer cells in promoting this process. Immunotherapy works through stimulation of the immune system by active immunization with cancer vaccines, or passive immunization through tumor-specific antibodies and immune modulators. Our aim is to highlight the importance of immunotherapy. This therapy gives patients (with breast cancer ) a better quality of life even at advanced stages of cancer. Immunotherapy may replace chemotherapy as the standard treatment for cancer in the fore coming future.
Key words: BREAST CANCER, IMMUNOTHERAPY TREATMENTS, ESTROGEN, CHEMOTHERAPY, VACCINES, INTERLEUKIN, T-LYMPHOCYTES, MONOCYTES, MONOCLONAL ANTIBODIES
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