Abstract
An: 2019, Nr.2, Articol Nr. 8
Title: 

CARCINOID HEART DISEASE AND CARDIAC METASTASIS IN NEUROENDOCRINE TUMORS: INSIGHTS FROM PATHOLOGY TO PERSONALISED DIAGNOSTIC AND THERAPEUTIC APPROACH

Authors: 

      Cati Raluca Stolniceanu, Irena Cristina Grierosu, Mihai Gutu, Cipriana Stefanescu - “Grigore T. Popa” University of Medicine and Pharmacy, Iasi, Romania, Biophysics and Medical Physics Department; “St. Spiridon” Emergency County Hospital, Iasi, Romania, Nuclear Medicine Laboratory
      Wael Jalloul - “St. Spiridon” Emergency County Hospital, Iasi, Romania, Nuclear Medicine Laboratory
      Volovat Constantin, Volovat Simona - “Grigore T. Popa University of Medicine and Pharmacy, Iasi, Romania, Oncology Department
      Carmen Delianu - “Grigore T. Popa University of Medicine and Pharmacy, Iasi, Romania
      Irina Nedelcu - “St. Spiridon” Emergency County Hospital, Iasi, Romania, ENT Department
      Milovan Matovic - Center for Nuclear Medicine, Serbia, Clinical Center Kragujevac; University of Kragujevac, Serbia, Faculty of Medical Sciences
      CARCINOID HEART DISEASE AND CARDIAC METASTASIS IN NEUROENDOCRINE TUMORS: INSIGHTS FROM PATHOLOGY TO PERSONALISED DIAGNOSTIC AND THERAPEUTIC APPROACH (Abstract): Carcinoid heart disease is produced by the paraneoplastic issue of the vasoactive substances excreted by the tumor, especially serotonin and represents a major cause of mortality in patients with metastatic neuroendocrine tumors. It has been observed that approximately 50% from patients with the carcinoid syndrome occurred will develop carcinoid heart disease. Carcinoid heart disease and neuroendocrine tumors cardiac metastases and are two different items, none of ethers affect the others. Ordinarily, myocardium metastases are not often seen. The prognosis of neuroendocrine tumors patients with confirmed carcinoid heart disease has improved over the past few decades, due to the upgrading in the cardiac imaging technologies, antitumor therapies, perioperative management and cardiac surgery. A multidisciplinary approach is necessary for the complex management of patients with carcinoid heart disease, both for the systemic malignant disease and the cardiac involvement.
Key words: CARCINOID HEART DISEASE, NEUROENDOCRINE TUMORS, CARDIAC METASTASIS
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