Abstract
An: 2017, Nr.1, Articol Nr. 10
Title:
RENAL SUBCAPSULAR VASCULAR LEIOMYOMA: A CASE REPORT AND REVIEW OF RELEVANT LITERATURE
Authors:
T. Ţăranu, C.I. Stan, M. Moraru, Delia Hînganu, M. Hînganu - “Grigore T. Popa” University of Medicine and Pharmacy, Iaşi, Romania, Faculty of Medicine, Department Morpho-Functional Sciences (I)
A.H. Nedelcu - “Grigore T. Popa” University of Medicine and Pharmacy, Iaşi, Romania, Faculty of Medicine, Department Morpho-Functional Sciences (I); “Sf. Spiridon” Universitary Hospital Iasi, Department of Diagnosis Radiology
Ludmila Lozneanu - “Sf. Spiridon” Universitary Hospital Iasi, Department of Morphopathology
B. Ciuntu - “Sf. Spiridon” Universitary Hospital Iasi, Department of Surgery
Tatiana Ţăranu - Railways Universitary Hospital, Iasi, Department of Dermatology
RENAL SUBCAPSULAR VASCULAR LEIOMYOMA:A CASE REPORT AND REVIEW OF RELEVANT LITERATURE (Abstract): Background: Primary renal leiomyoma was confirmed as a rare benign tumor formed by smooth muscle fibers and usually asymptomatic. Purpose: to describe a subcapsular cortical renal leiomyoma with probable vascular origin. Materials and methods: case report of a patient with pain in the left flank with imaging exploration (ultrasonoangiography, abdominal CT and MRI) and microscopic and immunohistochemically postoperatively evaluation. Results: a well-defined solid nodular tumor of about 40mm×50mm×45mm was observed in the upper polar renal cortex, beneath the renal capsule. The tumor mass was poorly vascularized, non-invasive and of benign aspect, hypoechogenic and isodense with renal cortex, with hypo intense heterogeneous signal in T2-weighted image, with fibrous/muscular aspect, and central hypodense area (potential necrosis). Histopathology (fusiform bundled smooth muscle cells) and immunohistochemistry of the tumor cells (positive to actin and negative to MB45) supported the diagnosis of renal leiomyoma. Postoperative evolution was normal at 3 months with no recurrence. Conclusions: Histopathology results confirmed the vascular origin for subscapular leiomyoma. Intratumoral necrosis is associated to degenerative lesions of the muscle fibers. The present tumor mass had an absolute surgical indication.
Key words: RENAL LEIOMYOMA, COMPUTED TOMOGRAPHY, MAGNETIC RESONANCE IMAGING, IMMUNOHISTOPATOLOGY
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