Abstract
An: 2015, Nr.1, Articol Nr. 6
Title: 

COMPARISON OF MORPHOCLINICAL CHARACTERISTICS OF GIANT CELL AORTITIS AND TAKAYASU AORTITIS IN PATIENTS WITH ASCENDING AORTIC ANEURYSM

Authors: 

      Doina Butcovan - Institute of Cardiovascular Diseases, “Prof. Dr. George I.M. Georgescu”, Iaşi, Romania; University of Medicine and Pharmacy “Grigore T. Popa”, Iaşi, Romania, Department of Morpho Functional Sciences
      Raluca Ozana Chistol, Flavia Antoniu - Institute of Cardiovascular Diseases, “Prof. Dr. George I.M. Georgescu”, Iaşi, Romania
      Cristina Furnică - University of Medicine and Pharmacy “Grigore T. Popa”, Iaşi, Romania, Department of Morpho Functional Sciences
      Gr. Tinică - Institute of Cardiovascular Diseases, “Prof. Dr. George I.M. Georgescu”, Iaşi, Romania; University of Medicine and Pharmacy “Grigore T. Popa”, Iaşi, Romania, Department of Surgery
      COMPARISON OF MORPHOCLINICAL CHARACTERISTICS OF GIANT CELL AORTITIS AND TAKAYASU AORTITIS IN PATIENTS WITH ASCENDING AORTIC ANEURYSM (Abstract): Giant cell aortitis is a relatively common condition, but its differentiation from the rarer Takayasu aortitis still poses challenges for most specialists. In this study we attempted to draw a comparison between the distinct characteristics of giant cell aortitis and Takayasu aortitis. The clinical, paraclinical and pathological data of the two diagnoses was obtained through the clinical assessment and histological study of surgically excised ascending aortas. The concerned patients, both of them females, (the Takayasu aortitis case at 36 years of age and Giant cell aortitis at 59 years, respectively) presented the same clinical picture of aortic aneurysm formation, with a singular difference: in the Takayasu aortitis, the subclavian artery was also affected. After a first closer examination the two disorders present a greater number of similarities: imaging studies have revealed aortic dilation in both patients and histopathological study of arterial lesions, represented by aortic granulomatous inflammation, was in both cases was indistinguishable. The rupture of the inflammatory aortic aneurysm, also revealed on both Takayasu and giant cell aortitis, is aknownledged in literature as a common feature for both these 2 life-treating aortitis. In conclusion, an early diagosis, proper medical treatment, and periodical life-long controls of patients with diagnosed Giant cell aortitis and Takayasu aortitis can prevent severe complications such as aortal aneurysm rupture.
Key words: GIANT CELL AORTITIS, TAKAYASU AORTITIS, AORTIC ANEURYSM GCA GIANT CELL AORTITIS TA TAKAYASU AORTITIS
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